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KMID : 0438219790160030471
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Korea University Medical Journal
1979 Volume.16 No. 3 p.471 ~ p.475
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Distribution of Antibodies to Korean Hemorrhagic Fever Virus in Korean
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Abstract
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Epidemic hemorrhagic fever was recognized for the first time in Korea in 1951 and has since been known as Korean hemorrhagic fever (KHF). Hemorrhagic fevers with a similar syndrome to KHF are being reported from many parts of the world.
Recently the etiologic agent of KHF was isolated by Lee et al, and the natural reservoir was demonstrated as Apodenms agrarius coreae. The serological diagnosis has also becomes available by means of the immunofluorescent antibody technique.
Distribution of antibodies to KHF virus among residents of hyper-endemic areas, residents of near endemic areas and non-endemic areas were studied serologically for the first time and results obtained are summarized as following.
1. Six out of 148 residents in hyper-endemic areas of Pochun have contained antibodies to KHF virus (4.0%). All of 6 positives were in age range of 20-40, and 4 of them-were female.
2. Two out of 73 residents in near endemic areas of Chunchun have contained antibodies to KHF virus (2.7%). All of 2 positives were in age range of 21-50, and 1 of them was male.
3, Only 1 out of 132 residents in non-endemic areas of Seoul was positive against KHF. virus (0.8%) and she was in age range of 51-60.
The above results indicate serologically for the first time that distribution of antibodies to KHF virus among Korean was less than 4.0% and there was no sex difference in incidence of KHF.
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KEYWORD
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